Hericium erinaceus (Lion’s Mane) Mycelium Ameliorates In Vivo Progression of Osteoarthritis

Immune System Support /

Shang-Yu Yang,1,† Chi-Jung Fang,2,† Yu-Wen Chen,3 Wan-Ping Chen,3 Li-Ya Lee,3 Chin-Chu Chen,4,5,6 Yen-You Lin,7 Shan-Chi Liu,8 Chun-Hao Tsai,9,10 Wei-Chien Huang,11,12 Yang-Chang Wu,13,14 and Chih-Hsin Tang7,11,15,16,* Keywords: osteoarthritis, Hericium erinaceus, mycelium, anterior cruciate ligament transection, interleukin 1 beta, tumor necrosis factor-alpha Abstract Osteoarthritis (OA) is an age-related disorder that affects the joints and causes functional disability. Hericium erinaceus is a large edible mushroom with several known medicinal functions. However, the therapeutic effects […]

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Ganoderma tsugae prevents cognitive impairment and attenuates oxidative damage in d-galactose-induced aging in the rat brain

Alzheimers Prevention / Treatment /

Hui-Chuan Kuo, Data curation, Formal analysis, Resources, Validation, Writing – original draft,# 1 Sih-Yu Tong, Data curation, Formal analysis, Methodology, Writing – original draft,# 2 Ming-Wei Chao, Data curation, Formal analysis, Methodology, Resources, Writing – original draft,# 3 and Chia-Yi Tseng, Conceptualization, Formal analysis, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing 2  Yasmina Abd‐Elhakim, Editor Abstract Lingzhi has long been regarded as having life-prolonging effects. Research in recent years has also reported that Lingzhi possesses anti-tumor, anti-inflammatory, immunomodulatory, hepatoprotective,

Ganoderma tsugae prevents cognitive impairment and attenuates oxidative damage in d-galactose-induced aging in the rat brain Read More »

The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro

Cancer prevention / treatments /

Rocky Lowenthal,a Megan Taylor,a Jennifer A. Gidden,b Billie Heflin,a Jackson O. Lay, Jr,b,c Nathan Avaritt,a Alan J. Tackett,a,* and Alicja Urbaniaka,* Keywords: Melanoma, Trametes versicolor, Coriolus versicolor, Mushroom, Turkey tail Abstract Melanoma is one of the most aggressive forms of skin cancer and is characterized by high metastatic potential. Despite improvements in early diagnosis and treatment, the mortality rate among metastatic melanoma patients continues to represent

The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro Read More »

Modulation of the Gut Microbiota with Prebiotics and Antimicrobial Agents from Pleurotus ostreatus (Oyster) Mushroom

Immune System Support /

Gréta Törős 1 2, Hassan El-Ramady 3, József Prokisch 1, Fernando Velasco 1, Xhensila Llanaj 1 4, Duyen H H Nguyen 1 4 5, Ferenc Peles 6 Keywords: prebiotics, probiotics, Pleurotus ostreatus polysaccharides, phenolic compounds, terpenoids, lectins, oyster extracts, secondary metabolies Abstract Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm mushroom contains bioactive compounds with both antimicrobial and prebiotic properties, which are distributed in the mushroom mycelium, fruiting body, and spent substrate. The mushroom is rich in

Modulation of the Gut Microbiota with Prebiotics and Antimicrobial Agents from Pleurotus ostreatus (Oyster) Mushroom Read More »

Medicinal Fungi with Antiviral Effect (Reishi and others)

Immune System Support /

Yu Zhang,1 Guoying Zhang,1,* and Jianya Ling1,2,* Mourad Elhabiri, Academic Editor Abstract Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal

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Puffball spores improve wound healing in a diabetic rat model

Diabetes Prevention / Treatment /

Tangtang He, 1 , 2 , 3 Pengfei Sun, 1 , 3 Bo Liu, 1 , 3 Shiwei Wan, 1 , 2 , 3 Penghua Fang, 2 , 3 Jun Chen, 4 Guicheng Huang, 1 , 3 , * and Wen Min Keywords: diabetic wound ulcer, Puffball spores, oxidative stress, wound healing, angiogenesis Abstract Persistent chronic oxidative stress is a primary pathogenic characteristics of diabetic foot ulcers. Puffball spores are a traditional Chinese medicine used to treat diabetic foot ulcers

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A polysaccharide-peptide with mercury clearance activity from dried fruiting bodies of Maitake mushroom Grifola frondosa

Toxicology /

Weiwei Zhang,#1,2Xuezhen Jiang,#2Shuang Zhao,#3Xiaojie Zheng,2Jin Lan,1Hexiang Wang,2 and Tzi Bun Ng4 Mercury is considered to be “a global pollutant” and raises concern worldwide. Once mercury enters the body, it will be distributed all over the body but will accumulate in the brain, kidney and liver. To date, no substance originating from edible fungi capable of adsorbing mercury

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Lead detoxification of edible fungi Auricularia auricula and Pleurotus ostreatus: the purification of the chelation substances and their effects on rats (Wood Ear and Oyster Mushrooms)

Toxicology /

Weiwei Zhang,# 1 , 2 , † Xiaojie Zheng,# 2 , † Xiangdong Chen, 1 Xuezhen Jiang, 2 Hexiang Wang, 2 , * and Guoqing Zhan Keywords: polysaccharide-peptide, lead clearance, chelation, antidotes, edible fungi Abstract Lead is a global pollutant that causes widespread concern. When a lead enters the body, it is distributed throughout the body and accumulates in the brain, bone, and soft tissues such as the kidney, liver, and

Lead detoxification of edible fungi Auricularia auricula and Pleurotus ostreatus: the purification of the chelation substances and their effects on rats (Wood Ear and Oyster Mushrooms) Read More »

Vitamin B12-Containing Plant Food Sources for Vegetarians (Shiitake and others)

Immune System Support /

Fumio Watanabe,* Yukinori Yabuta, Tomohiro Bito, and Fei Teng Abstract The usual dietary sources of Vitamin B12 are animal-derived foods, although a few plant-based foods contain substantial amounts of Vitamin B12. To prevent Vitamin B12 deficiency in high-risk populations such as vegetarians, it is necessary to identify plant-derived foods that contain high levels of Vitamin B12. A survey of naturally

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Isolation, Characterization, and Medicinal Potential of Polysaccharides of Morchella esculenta (Yellow Morel)

Immune System Support /

Abstract Mushroom polysaccharides are active medicinal compounds that possess immune-modulatory and anticancer properties. Currently, the mushroom polysaccharides krestin, lentinan, and polysaccharopeptides are used as anticancer drugs. They are an unexplored source of natural products with huge potential in both the medicinal and nutraceutical industries. The northern parts of Pakistan have a rich biodiversity of mushrooms

Isolation, Characterization, and Medicinal Potential of Polysaccharides of Morchella esculenta (Yellow Morel) Read More »

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