Shang-Yu Yang,1,† Chi-Jung Fang,2,† Yu-Wen Chen,3 Wan-Ping Chen,3 Li-Ya Lee,3 Chin-Chu Chen,4,5,6 Yen-You Lin,7 Shan-Chi Liu,8 Chun-Hao Tsai,9,10 Wei-Chien Huang,11,12 Yang-Chang Wu,13,14 and Chih-Hsin Tang7,11,15,16,* Keywords: osteoarthritis, Hericium erinaceus, mycelium, anterior cruciate ligament transection, interleukin 1 beta, tumor necrosis factor-alpha Abstract Osteoarthritis (OA) is an age-related disorder that affects the joints and causes functional disability. Hericium erinaceus is a large edible mushroom with several known medicinal...

Gréta Törős 1 2, Hassan El-Ramady 3, József Prokisch 1, Fernando Velasco 1, Xhensila Llanaj 1 4, Duyen H H Nguyen 1 4 5, Ferenc Peles 6 Keywords: prebiotics, probiotics, Pleurotus ostreatus polysaccharides, phenolic compounds, terpenoids, lectins, oyster extracts, secondary metabolies Abstract Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm mushroom contains bioactive compounds with both antimicrobial and prebiotic properties, which are distributed in the mushroom mycelium, fruiting body, and spent substrate....

Yu Zhang,1 Guoying Zhang,1,* and Jianya Ling1,2,* Mourad Elhabiri, Academic Editor Abstract Pandemics from various viruses make natural organisms face challenges over and over again. Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is...

Fumio Watanabe,* Yukinori Yabuta, Tomohiro Bito, and Fei Teng Abstract The usual dietary sources of Vitamin B12 are animal-derived foods, although a few plant-based foods contain substantial amounts of Vitamin B12. To prevent Vitamin B12 deficiency in high-risk populations such as vegetarians, it is necessary to identify plant-derived foods that contain high levels of Vitamin...

Abstract Mushroom polysaccharides are active medicinal compounds that possess immune-modulatory and anticancer properties. Currently, the mushroom polysaccharides krestin, lentinan, and polysaccharopeptides are used as anticancer drugs. They are an unexplored source of natural products with huge potential in both the medicinal and nutraceutical industries. The northern parts of Pakistan have...

Mendel FriedmanCharles Brennan, Academic Editor Abstract More than 2000 species of edible and/or medicinal mushrooms have been identified to date, many of which are widely consumed, stimulating much research on their health-promoting properties. These properties are associated with bioactive compounds produced by the mushrooms, including polysaccharides. Although β-glucans (homopolysaccharides) are believed...

Shuang Zhao,1 Qi Gao,1 Chengbo Rong,1 Shouxian Wang,1 Zhekun Zhao,1,2 Yu Liu,1 and Jianping Xu3,* Abstract   Mushrooms have been valued as food and health supplements by humans for centuries. They are rich in dietary fiber, essential amino acids, minerals, and many bioactive compounds, especially those related to human immune system functions. Mushrooms contain diverse immunoregulatory compounds...

Md Asaduzzaman Khan 1, Mousumi Tania, Rui Liu, Mohammad Mijanur Rahman   Abstract Mushrooms are considered as nutritionally functional foods and source of physiologically beneficial medicines. Hericium erinaceus, also known as Lion’s Mane Mushroom or Hedgehog Mushroom, is an edible fungus, which has a long history of usage in traditional Chinese medicine. This mushroom...