Rocky Lowenthal,a Megan Taylor,a Jennifer A. Gidden,b Billie Heflin,a Jackson O. Lay, Jr,b,c Nathan Avaritt,a Alan J. Tackett,a,* and Alicja Urbaniaka,* Keywords: Melanoma, Trametes versicolor, Coriolus versicolor, Mushroom, Turkey tail Abstract Melanoma is one of the most aggressive forms of skin cancer and is characterized by high metastatic potential. Despite improvements in early diagnosis and treatment, the mortality rate among metastatic...

Mendel FriedmanCharles Brennan, Academic Editor Abstract More than 2000 species of edible and/or medicinal mushrooms have been identified to date, many of which are widely consumed, stimulating much research on their health-promoting properties. These properties are associated with bioactive compounds produced by the mushrooms, including polysaccharides. Although β-glucans (homopolysaccharides) are believed...

Rongchen Dai,1,† Mengfan Liu,1,† Wan Najbah Nik Nabil,1,2 Zhichao Xi,1,* and Hongxi Xu3,* Abstract   Mycomedicine is a unique class of natural medicine that has been widely used in Asian countries for thousands of years. Modern mycomedicine consists of fruiting bodies, spores, or other tissues of medicinal fungi, as well as bioactive components extracted from...

  Solomon Habtemariam 1 Abstract Coriolus versicolor (L.) Quél. is a higher fungi or mushroom which is now known by its accepted scientific name as Trametes versicolor (L.) Lloyd (family Polyporaceae). The polysaccharides, primarily two commercial products from China and Japan as PSP and PSK, respectively, have been claimed to serve as adjuvant therapy...

Excerpt PDQ Integrative, Alternative, and Complementary Therapies Editorial Board This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of medicinal mushrooms in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians in the care of...

Excerpt PDQ Integrative, Alternative, and Complementary Therapies Editorial Board This PDQ cancer information summary has current information about the use of medicinal mushrooms in the treatment of people with cancer. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for...

  YingYing He 1, Shubai Liu 2, David S Newburg 3 Abstract Colorectal cancer is the second deadly cancer in the world. Trametes versicolor is a traditional Chinese medicinal mushroom with a long history of being used to regulate immunity and prevent cancer. Trametes versicolor mushroom extract demonstrates strongly cell growth inhibitory activity on human...

Grifola frondosa Barrie R. Cassileth, MS, PhD Maitake beta- glucan extract obtained from the fruiting bodies of maitake mushroom, or Grifola frondosa, is widely used in Asia as a cancer treatment, typically adjunctively. Research to determine the mechanisms that underlie maitake’s anticancer effects is ongoing, as detailed at http://www.mskcc.org/AboutHerbs. Maitake...

Paola Rossi,1 Raffaele Difrancia,2 Vincenzo Quagliariello,3 Elena Savino,4 Paolo Tralongo,5 Cinzia Lucia Randazzo,6 and Massimiliano Berretta7 Abstract Culinary and medicinal mushrooms are widely used in Asian countries, both as dietary supplements and as nutraceutical foods. They have recently become popular in Europe, as well, for their nutritional and health benefits. In particular, epidemiological studies conducted in Asia...

  Noriko Kodama, Kiyoshi Komuta, and Hiroaki Nanba Abstract Maitake D-Fraction, extracted from maitake mushroom, has been reported to exert its antitumor effect in tumor-bearing mice by enhancing the immune system through activation of macrophages, T cells, and natural killer (NK) cells. In a previous study, the combination of immunotherapy with the...

Chao Liu,1,2 Yonghai Sun,1,* Qian Mao,1 Xiaolei Guo,1 Peng Li,2 Yang Liu,1 and Na Xu1 Li Lin, Academic Editor Abstract Polysaccharides from Morchella esculenta have been proven to be functional and helpful for humans. The purpose of this study was to investigate the chemical structure and anti-proliferating and antitumor activities of a Morchella esculenta polysaccharide (MEP) extracted by pulsed electric field...

  Ahmet Unlu 1, Erdinc Nayir, Onder Kirca, Mustafa Ozdogan Abstract Having a long historical past in traditional Chinese medicine, Ganoderma Lucidum (G. Lucidum) is a type of mushroom believed to extend life and promote health. Due to the increasing consumption pattern, it has been cultivated and marketed intensively since the 1970s. It is...